Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: a case-control study
www.thelancet.com/psychiatry
Published online February 18, 2015 http://dx.doi.org/10.1016/S2215-0366(14)00117-
FINDINGS: Between May 1, 2005, and May 31, 2011, we obtained data from 410 patients with first-episode psychosis and
370 population controls. The risk of individuals having a psychotic disorder showed a roughly three-times increase in
users of skunk-like cannabis compared with those who never used cannabis (adjusted odds ratio [OR] 2·92, 95% CI
1·52–3·45, p=0·001). Use of skunk-like cannabis every day conferred the highest risk of psychotic disorders compared
with no use of cannabis (adjusted OR 5·4, 95% CI 2·81–11·31, p=0·002). The population attributable fraction of first-
episode psychosis for skunk use for our geographical area was 24% (95% CI 17–31), possibly because of the high
prevalence of use of high-potency cannabis (218 [53%] of 410 patients) in our study.
Read more here
http://learnaboutsam.org/wp-content/uploads/2015/02/Marta-PAF-paper-Lancet-Psychiatry-1.pdf
http://www.webmd.boots.com/mental-health/news/20150216/skunk-cannabis-psychosis-risk
Published online February 18, 2015 http://dx.doi.org/10.1016/S2215-0366(14)00117-
FINDINGS: Between May 1, 2005, and May 31, 2011, we obtained data from 410 patients with first-episode psychosis and
370 population controls. The risk of individuals having a psychotic disorder showed a roughly three-times increase in
users of skunk-like cannabis compared with those who never used cannabis (adjusted odds ratio [OR] 2·92, 95% CI
1·52–3·45, p=0·001). Use of skunk-like cannabis every day conferred the highest risk of psychotic disorders compared
with no use of cannabis (adjusted OR 5·4, 95% CI 2·81–11·31, p=0·002). The population attributable fraction of first-
episode psychosis for skunk use for our geographical area was 24% (95% CI 17–31), possibly because of the high
prevalence of use of high-potency cannabis (218 [53%] of 410 patients) in our study.
Read more here
http://learnaboutsam.org/wp-content/uploads/2015/02/Marta-PAF-paper-Lancet-Psychiatry-1.pdf
http://www.webmd.boots.com/mental-health/news/20150216/skunk-cannabis-psychosis-risk